Defining the phenotype and prognosis of people with idiopathic intracranial hypertension after cerebrospinal fluid diversion surgery.
Hyder, Yousef F Homer, Victoria Thaller, Mark Byrne, Marian Tsermoulas, Georgios Piccus, Rachel Mollan, Susan P Sinclair, Alexandra J
Hyder, Yousef F
Homer, Victoria
Thaller, Mark
Byrne, Marian
Tsermoulas, Georgios
Piccus, Rachel
Mollan, Susan P
Sinclair, Alexandra J
Abstract
Fifty-one patients without previous surgical interventions were included (92% female, mean age 28.1 years [SD 8.4], body mass index 37.4 kg/m2 [SD 9.7], mean days of follow-up 330 [SD 209]). Measurements before surgery showed mean PMD -11.4 dB (SD 9.7), RNFL 364 µm (SD 128), Frisén grade papilledema 4.3 (SD 0.9). and MHD 23 (SD 10.6). At 1 month postoperatively, RNFL and PMD had improved by 38% and 4%, respectively. At 4 months postoperatively, papilledema had resolved. GCL declined by 13% over 12 months. MHD reduced by 75% 3 months postoperatively before returning to baseline levels by 12 months. Five patients (9.8%) required revision surgeries.
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Date
2023-01-20
Type
Article
Subject
Neurology, Ophthalmology
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Citation
Hyder YF, Homer V, Thaller M, Byrne M, Tsermoulas G, Piccus R, Mollan SP, Sinclair AJ. Defining the Phenotype and Prognosis of People With Idiopathic Intracranial Hypertension After Cerebrospinal Fluid Diversion Surgery. Am J Ophthalmol. 2023 Jun;250:70-81. doi: 10.1016/j.ajo.2023.01.016. Epub 2023 Jan 20. PMID: 36682516.
Journal / Source Title
American Journal of Ophthalmology
DOI
10.1016/j.ajo.2023.01.016
PMID
36682516
Publisher
Elsevier
Publisher’s URL
https://www.ajo.com/article/S0002-9394(23)00026-0/fulltext