Allergic diseases in India - prevalence, risk factors and current challenges.
Mahesh, Padukudru Anand Moitra, Saibal Mabalirajan, Ulaganathan Garg, Mayank Malamardi, Sowmya Vedanthan, Pudupakkam K Christopher, Devasahayam Jesudas Agrawal, Anurag Krishna, Mamidipudi Thirumala
Mahesh, Padukudru Anand
Moitra, Saibal
Mabalirajan, Ulaganathan
Garg, Mayank
Malamardi, Sowmya
Vedanthan, Pudupakkam K
Christopher, Devasahayam Jesudas
Agrawal, Anurag
Krishna, Mamidipudi Thirumala
Abstract
Epidemiological studies have shown a rise in the prevalence of allergic diseases in India during the last two decades. However, recent evidence from the Global Asthma Network study has observed a decrease in allergic rhinitis, asthma and atopic dermatitis in children. Still, with a population over 1.3 billion, there is a huge burden of allergic rhinitis, asthma and atopic dermatitis, and this is compounded by an unmet demand for trained allergy specialists and poor health service framework. There is wide variation in the prevalence of allergic diseases between different geographical locations in India, and the reasons are unclear at present. This may at least in part be attributable to considerable heterogeneity in aero-biology, weather, air pollution levels, cultural and religious factors, diet, socioeconomic strata and literacy. At present, factors enhancing risks and those protecting from development of atopy and allergic diseases have not been well delineated, although there is some evidence for the influence of genetic factors alongside cultural and environmental variables such as diet, exposure to tobacco smoke and air pollution and residence in urban areas. This narrative review provides an overview of data from India regarding epidemiology, risk factors and genetics and highlights gaps in evidence as well as areas for future research.
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Date
2022-10-24
Type
Article
Subject
Respiratory medicine
Citation
Mahesh PA, Moitra S, Mabalirajan U, Garg M, Malamardi S, Vedanthan PK, Christopher DJ, Agrawal A, Krishna MT. Allergic diseases in India - Prevalence, risk factors and current challenges. Clin Exp Allergy. 2023 Mar;53(3):276-294. doi: 10.1111/cea.14239. Epub 2022 Oct 24.
Journal / Source Title
Clinical and Experimental Allergy
DOI
10.1111/cea.14239
PMID
36181726
Publisher
Wiley
Publisher’s URL
https://onlinelibrary.wiley.com/journal/13652222