COVID-19 vaccines are effective at preventing symptomatic and severe infection among healthcare workers: a clinical review.
Abstract
Participants included were predominantly female and working age. Median time to infection was 51 days. Reported vaccine effectiveness against infection, symptomatic infection, and infection requiring hospitalisation were between 5 and 100 %, 34 and 100 %, and 65 and 100 % (respectively). No vaccinated HCW deaths were recorded in any study. Pooled estimates of protection against infection, symptomatic infection, and hospitalisation were, respectively, 84.7 % (95 % CI 72.6-91.5 %, p < 0.0001), 86.0 % (95 % CI 67.2 %-94.0 %; p < 0.0001), and 96.1 % (95 % CI 90.4 %-98.4 %). Waning protection against infection was reported by four studies, although protection against hospitalisation for severe infection persists for at least 6 months post vaccination.
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Date
2024-08-05
Type
Article
Other
Other
Subject
Public health. Health statistics. Occupational health. Health education, Communicable diseases, Microbiology. Immunology
Collections
Citation
Galgut O, Ashford F, Deeks A, Ghataure A, Islam M, Sambhi T, Ker YW, Duncan CJA, de Silva TI, Hopkins S, Hall V, Klenerman P, Dunachie S, Richter A. COVID-19 vaccines are effective at preventing symptomatic and severe infection among healthcare workers: A clinical review. Vaccine X. 2024 Aug 5;20:100546. doi: 10.1016/j.jvacx.2024.100546.
Journal / Source Title
Vaccine: X
DOI
10.1016/j.jvacx.2024.100546
PMID
39221179
Publisher
Elsevier Ltd.
Publisher’s URL
https://www.sciencedirect.com/journal/vaccine-x