Recurrent severe respiratory infections with low CRP secondary to autoimmune IL-6 deficiency.
Hackney, Alexander James, Sunil Karanam, Surendra
Hackney, Alexander
James, Sunil
Karanam, Surendra
Abstract
C reactive protein (CRP) is an inflammatory protein that is often used in conjunction with the clinical presentation of a patient to help with quantifying infection severity and measuring treatment response. We report the case of a patient who presented with severe pneumonias but had a suboptimal CRP response, later diagnosed as having an underlying immunodeficiency. This case exemplifies the need to consider immunodeficiency as an underlying pathophysiological cause in patients presenting with complicated and severe infections.
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Date
2021-06-21
Type
Article
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Citation
Hackney A, James S, Karanam S. Recurrent severe respiratory infections with low CRP secondary to autoimmune IL-6 deficiency. BMJ Case Rep. 2021 Jun 21;14(6):e243334. doi: 10.1136/bcr-2021-243334.
Journal / Source Title
DOI
10.1136/bcr-2021-243334
PMID
34155030
Publisher
BMJ Publishing Group