The physiology of extracorporeal membrane oxygenation: the Fick principle.
Lim, Hoong
Lim, Hoong
Abstract
Extracorporeal membrane oxygenation (ECMO) can be delivered in veno-arterial (VA) and veno-venous (VV) configurations based on the cannulation strategy. VA and VV ECMO are delivered primarily for haemodynamic and respiratory support in patients with severe heart and lung failure, respectively. The Fick principle describes the relationship between blood flow and oxygen consumption - key parameters in the physiological management of extracorporeal support. This review will discuss the application of the Fick principle in: (i) recirculation in VV ECMO; (ii) the quantification of oxygen delivery (DO2) in VV ECMO and (iii) the quantification of transpulmonary blood flow and systemic arterial oxygen saturation in VA ECMO.
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Date
2021-12-27
Type
Article
Subject
Haematology
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Citation
Lim H. The physiology of extracorporeal membrane oxygenation: The Fick principle. Perfusion. 2023 Mar;38(2):236-244. doi: 10.1177/02676591211055971. Epub 2021 Dec 27
Journal / Source Title
Perfusion
DOI
10.1177/02676591211055971
PMID
34961381
Publisher
SAGE Publications
Publisher’s URL
https://journals.sagepub.com/home/prf