Comparing the audiological success of bone cement to standard ossiculoplasty techniques: a systematic review and meta-analysis
Abstract
Objective: To compare the audiological success and longevity of bone cement to standard ossiculoplasty techniques.
Data sources: PubMed, Embase, Cochrane Library, Medline, and the Web of Science were systematically searched for studies from the date of inception to November 8, 2024.
Review methods: Two independent reviewers screened for eligibility. Inclusion criteria were full-text, English language publications. Human studies of any methodology except case series with fewer than five patients were included. The Preferred Reporting Items for Systematic Reviews and Meta-analyses reporting guidelines were followed. Data were pooled using a random-effects model using relative risk with 95% CIs. Prespecified primary outcomes compared the success of bone cement reconstruction at short and longer-term follow-up.
Results: A total of 27 studies met the eligibility criteria. Bone cement resulted in better audiological outcomes (postoperative mean air-bone gap < 20 dB HL) compared to incus interposition, risk ratio (RR): 1.26 (95% CI: 1.10-1.43). There was no difference in success between bone cement and partial ossicular replacement prosthesis (PORP), RR: 1.15 (95% CI: 0.94-1.41). The findings of this review suggest that bone cement remains successful at a longer-term follow-up.
Conclusion: Bone cement outperforms incus interposition and is comparable to PORP for audiological outcomes. Audiological improvement is sustained into longer-term follow-up.
Date
2025-07-22
Type
Article
Subject
Ear, Nose & Throat, Surgery
Collections
Citation
Dowell N, Begum S, Coulson C, Nieto H, Muzaffar J. Comparing the Audiological Success of Bone Cement to Standard Ossiculoplasty Techniques: A Systematic Review and Meta-analysis. Otolaryngol Head Neck Surg. 2025 Nov;173(5):1054-1068. doi: 10.1002/ohn.1356. Epub 2025 Jul 22.
Journal / Source Title
Otolaryngology - Head and Neck Surgery
DOI
10.1002/ohn.1356
PMID
40693566
Publisher
Wiley
Publisher’s URL
https://aao-hnsfjournals.onlinelibrary.wiley.com/journal/10976817