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Platypnoea orthodeoxia syndrome and its association with cryptogenic ischaemic stroke

Salam A
Mandal S
Fathima S
Rasthapuram S
Radhakrishnan K.
Abstract
Platypnoea orthodeoxia syndrome is a rare condition, which can be present in patients with patent foramen ovale (PFO). In this case, a 72-year-old lady presented to the emergency department with a cryptogenic stroke associated with right thalamic infarct. While in hospital, it was noticed that the patient had desaturations in the upright position, and these improved in the recumbent position, consistent with platypnoea orthodeoxia syndrome. The patient was found to have a PFO, which was then closed, and her saturations returned to normal. This case highlights the importance of patients who present with cryptogenic stroke and features of platypnoea orthodeoxia syndrome need to be considered for underlying PFO or other septal defect.
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Date
2023-03-04
Type
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Neurology
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Citation
Salam A, Mandal S, Fathima S, Rasthapuram S, Radhakrishnan K. Platypnoea orthodeoxia syndrome and its association with cryptogenic ischaemic stroke. J R Coll Physicians Edinb. 2023 Jun;53(2):109-110. doi: 10.1177/14782715231159470. Epub 2023 Mar 4. PMID: 36869700.
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DOI
10.1177/14782715231159470
PMID
36869700
Publisher
Sage
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