Factors influencing implementation and adoption of direct oral penicillin challenge for allergy delabelling: a qualitative evaluation
Jani, Yogini H Williams, Iestyn McErlean, Mairead Bhogal, Rashmeet Ng, Bee Yean Kildonaviciute, Kornelija Balaji, Ariyur Daniels, Ron Dunsmure, Louise Hullur, Chidanand
Jani, Yogini H
Williams, Iestyn
McErlean, Mairead
Bhogal, Rashmeet
Ng, Bee Yean
Kildonaviciute, Kornelija
Balaji, Ariyur
Daniels, Ron
Dunsmure, Louise
Hullur, Chidanand
Abstract
Background: Over 95% of penicillin allergy labels are inaccurate and may be addressed in low-risk patients using direct oral penicillin challenge (DPC). This study explored the behaviour, attitudes and acceptability of patients, healthcare professionals (HCPs) and managers of using DPC in low-risk patients.
Methods: Mixed-method, investigation involving patient interviews and staff focus groups at three NHS acute hospitals. Transcripts were coded using inductive and deductive thematic analysis informed by the Theoretical Domains Framework.
Findings: Analysis of 43 patient interviews and three focus groups (28 HCPs: clinicians and managers) highlighted themes of 'knowledge', 'beliefs about capabilities and consequences', 'environmental context', 'resources', 'social influences', 'professional role and identity', 'behavioural regulation and reinforcement' and a cross-cutting theme of digital systems. Overall, study participants supported the DPC intervention. Patients expressed reassurance about being in a monitored, hospital setting. HCPs acknowledged the need for robust governance structures for ensuring clarity of roles and responsibilities and confidence.
Conclusion: There were high levels of acceptability among patients and HCPs. HCPs recognised the importance of DPC. Complexities of penicillin allergy (de)labelling were highlighted, and issues of knowledge, risk, governance and workforce were identified as key determinants. These should be considered in future planning and adoption strategies for DPC.
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Date
2024-09-07
Type
Article
Subject
Health services. Management, Anaesthesia, Communicable diseases, Microbiology. Immunology
Collections
Citation
Jani YH, Williams I, McErlean M, Bhogal R, Ng BY, Kildonaviciute K, Balaji A, Daniels R, Dunsmure L, Hullur C, Jones N, Misbah S, Pollard R, Powell N, Sandoe JAT, Thomas C, Warner A, West RM, Savic L, Thirumala Krishna M. Factors influencing implementation and adoption of direct oral penicillin challenge for allergy delabelling: a qualitative evaluation. BMJ Open Qual. 2024 Sep 7;13(3):e002890. doi: 10.1136/bmjoq-2024-002890
Journal / Source Title
BMJ Open Quality
DOI
10.1136/bmjoq-2024-002890
PMID
39244224
Publisher
BMJ Publishing Group
Publisher’s URL
http://bmjopenquality.bmj.com/