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Volume maximised glycerol rhizolysis for trigeminal neuralgia: a single centre analysis of outcomes.

Goel, Aimee
Kulkarni, Girish
Cotici, Alexandru
Paluzzi, Alessandro
Hayton, Tom
Chelvarajah, Ramesh
Abstract
37 procedures were carried out for typical trigeminal neuralgia, 13 for secondary trigeminal neuralgia, and 3 for atypical trigeminal neuralgia. Overall, pain freedom was achieved in 85% cases, and 92% in patients with typical trigeminal neuralgia. Median duration of pain freedom in patients with typical trigeminal neuralgia was 63 months, versus 6 months in those with secondary trigeminal neuralgia (p < 0.00001). 14 procedures (26.4%) resulted in mild and temporary complications. 54.7% of cases experienced hypoaesthesia in a distribution similar to or less extensive than the distribution of trigeminal neuralgia. The presence of hypoaesthesia post-procedure was highly predictive of longer pain freedom (95 months versus 8 months median pain freedom (p = 0.00003)).
Citation
Goel A, Kulkarni G, Cotici A, Paluzzi A, Hayton T, Chelvarajah R. Volume maximised glycerol rhizolysis for trigeminal neuralgia: a single centre analysis of outcomes. Br J Neurosurg. 2025 Apr;39(2):191-196. doi: 10.1080/02688697.2023.2207657. Epub 2023 May 5.
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