Physical properties and interaction with the ocular surface of water-gradient contact lenses
Abstract
Since the introduction of silicone hydrogel contact lenses, many silicone-hydrogel materials have been produced, including water-gradient contact lenses with a silicone hydrogel core and a thin hydrogel outer layer (e.g., delefilcon A, verofilcon A, and lehfilcon A). Their properties have been investigated in various studies assessing both the chemical-physical characteristics and the comfort, but the overall picture is not always consistent. In this study, water-gradient technology is reviewed by looking at basic physical properties both in vitro and in vivo and at the interaction with the human ocular surface. Surface and bulk dehydration, surface wetting and dewetting, shear stress, interaction with tear components and with other environmental compounds, and comfort are discussed.
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Date
2023-02-22
Type
Article
Subject
Ophthalmology
Citation
Ponzini E, Recchioni A, Cheloni R, Zeri F, Tavazzi S. Physical Properties and Interaction With the Ocular Surface of Water-Gradient Contact Lenses. Eye Contact Lens. 2023 Apr 1;49(4):152-159. doi: 10.1097/ICL.0000000000000974
Journal / Source Title
Eye & Contact Lens
DOI
10.1097/ICL.0000000000000974
PMID
36811833
Publisher
Lippincott, Williams & Wilkins