A service evaluation: impact of nurse-led regional familial hypercholesterolaemia service on a hospital adult lipid clinic.
Abstract
The authors evaluated the impact of genetic screening for familial hypercholesterolaemia (FH) in a lipid clinic cohort of patients with definite and possible FH as defined by the Simon Broome Register (SBR) criteria.
Methods: Patients with a lipid clinic diagnosis of definite and possible FH based on the SBR criteria were referred to a nurse-led regional service for FH genetic testing.
Findings: 140 patients were referred for genetic testing. Six had SBR-definite FH due to the presence of tendon xanthomata and 134 had SBR-possible FH. A monogenic FH mutation was detected in all six patients (100%) with SBR-definite FH and in 34 (25%) of patients with possible FH.
Conclusion: The appropriate use of molecular genetics in a lipid clinic will greatly facilitate the management of hyperlipidaemia and cardiovascular risk since the management of FH patients (National Institute for Health and Care Excellence (NICE) Clinical Guideline 71) is different from non-FH patients (NICE Clinical Guideline 181).
Citations
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Date
2020-11-12
Type
Article
Subject
Genetics, Pathology
Collections
Citation
Wilkinson B, George E, Horton S, Bellaby J, Min SS, Gama R. A service evaluation: impact of nurse-led regional familial hypercholesterolaemia service on a hospital adult lipid clinic. Br J Nurs. 2020 Nov 12;29(20):1206-1208. doi: 10.12968/bjon.2020.29.20.1206
Journal / Source Title
British Journal of Nursing (Mark Allen Publishing)
DOI
10.12968/bjon.2020.29.20.1206
PMID
33180610
Publisher
MA Healthcare
Publisher’s URL
http://www.magonlinelibrary.com/toc/bjon/current