British Gynaecological Cancer Society/British Association of Gynaecological Pathology consensus for germline and tumor testing for 1/2 variants in ovarian cancer in the United Kingdom.
Abstract
The British Gynecological Cancer Society and the British Association of Gynecological Pathologists established a multidisciplinary consensus group comprising experts in surgical gynecological oncology, medical oncology, genetics, and laboratory science, and clinical nurse specialists to identify the optimal pathways to BRCA germline and tumor testing in patients with ovarian cancer in routine clinical practice. In particular, the group explored models of consent, quality standards identified at pathology laboratories, and experience and data from pioneering cancer centers. The group liaised with representatives from ovarian cancer charities to also identify patient perspectives that would be important to implementation. Recommendations from these consensus group deliberations are presented in this manuscript.
Author
Sundar, Sudha
Manchanda, Ranjit
Gourley, Charlie
George, Angela
Wallace, Andrew
Balega, Janos
Williams, Sarah
Wallis, Yvonne
Edmondson, Richard
Nicum, Shibani
Frost, Jonathan
Attygalle, Ayoma
Fotopoulou, Christina
Bowen, Rebecca
Bell, Dani
Gajjar, Ketankumar
Ramsay, Bruce
Wood, Nicholas J
Ghaem-Maghami, Sadaf
Miles, Tracie
Ganesan, Raji
Manchanda, Ranjit
Gourley, Charlie
George, Angela
Wallace, Andrew
Balega, Janos
Williams, Sarah
Wallis, Yvonne
Edmondson, Richard
Nicum, Shibani
Frost, Jonathan
Attygalle, Ayoma
Fotopoulou, Christina
Bowen, Rebecca
Bell, Dani
Gajjar, Ketankumar
Ramsay, Bruce
Wood, Nicholas J
Ghaem-Maghami, Sadaf
Miles, Tracie
Ganesan, Raji
Citations
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Date
2021-01-19
Type
Article
Other
Other
Subject
Gynaecology
Collections
Citation
Sundar S, Manchanda R, Gourley C, George A, Wallace A, Balega J, Williams S, Wallis Y, Edmondson R, Nicum S, Frost J, Attygalle A, Fotopoulou C, Bowen R, Bell D, Gajjar K, Ramsay B, Wood NJ, Ghaem-Maghami S, Miles T, Ganesan R. British Gynaecological Cancer Society/British Association of Gynaecological Pathology consensus for germline and tumor testing for BRCA1/2 variants in ovarian cancer in the United Kingdom. Int J Gynecol Cancer. 2021 Feb;31(2):272-278. doi: 10.1136/ijgc-2020-002112. Epub 2021 Jan 19. Erratum in: Int J Gynecol Cancer. 2021 Dec;31(12):1619.
Journal / Source Title
International Journal of Gynecological Cancer
DOI
10.1136/ijgc-2020-002112
PMID
33468564
Publisher
BMJ Publishing Group