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Communication and Low Mood (CALM): a randomized controlled trial of behavioural therapy for stroke patients with aphasia
Thomas, Shirley A Walker, Marion F Macniven, Jamie A Haworth, Helen Lincoln, Nadina B
Thomas, Shirley A
Walker, Marion F
Macniven, Jamie A
Haworth, Helen
Lincoln, Nadina B
Abstract
Objective: The aim was to evaluate behavioural therapy as a treatment for low mood in people with aphasia.
Design: A randomized controlled trial comparing behavioural therapy plus usual care with a usual care control. Potential participants with aphasia after stroke were screened for the presence of low mood. Those who met the criteria and gave consent were randomly allocated.
Setting: Participants were recruited from hospital wards, community rehabilitation, speech and language therapy services and stroke groups.
Subjects: Of 511 people with aphasia identified, 105 had low mood and were recruited.
Interventions: Behavioural therapy was offered for up to three months. Outcomes were assessed three and six months after random allocation.
Main measures: Stroke Aphasic Depression Questionnaire, Visual Analog Mood Scales ‘sad’ item, and Visual Analogue Self-Esteem Scale.
Results: Participants were aged 29 to 94 years (mean 67.0, SD 13.5) and 66 (63%) were men. Regression analysis showed that at three months, when baseline values and communication impairment were controlled for, group allocation was a significant predictor of the Stroke Aphasic Depression Questionnaire (P < 0.05), visual analogue ‘sad’ (P = 0.03), and Visual Analogue Self-Esteem Scale (P < 0.01). At six months, group alone was a significant predictor of the Stroke Aphasic Depression Questionnaire (P < 0.05), and remained significant when baseline values were controlled for (P = 0.02). Mean Stroke Aphasic Depression Questionnaire 10-item hospital version scores decreased from baseline to six months by six points in the intervention group as compared with an increase of 1.9 points in the control group.
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2012-10-11
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Thomas SA, Walker MF, Macniven JA, Haworth H, Lincoln NB. Communication and Low Mood (CALM): a randomized controlled trial of behavioural therapy for stroke patients with aphasia. Clin Rehabil. 2013 May;27(5):398-408. doi: 10.1177/0269215512462227.
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© The Author(s) 2012
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DOI: 10.1177/0269215512462227
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