British Society for Echocardiography and British Cardio-Oncology Society guideline for transthoracic echocardiographic assessment of adult cancer patients receiving anthracyclines and/or trastuzumab
Abstract
The subspecialty of cardio-oncology aims to reduce cardiovascular morbidity and mortality in patients with cancer or following cancer treatment. Cancer therapy can lead to a variety of cardiovascular complications, including left ventricular systolic dysfunction, pericardial disease, and valvular heart disease. Echocardiography is a key diagnostic imaging tool in the diagnosis and surveillance for many of these complications. The baseline assessment and subsequent surveillance of patients undergoing treatment with anthracyclines and/or human epidermal growth factor (EGF) receptor (HER) 2-positive targeted treatment (e.g. trastuzumab and pertuzumab) form a significant proportion of cardio-oncology patients undergoing echocardiography. This guideline from the British Society of Echocardiography and British Cardio-Oncology Society outlines a protocol for baseline and surveillance echocardiography of patients undergoing treatment with anthracyclines and/or trastuzumab. The methodology for acquisition of images and the advantages and disadvantages of techniques are discussed. Echocardiographic definitions for considering cancer therapeutics-related cardiac dysfunction are also presented.
Author
Dobson, Rebecca
Ghosh, Arjun K
Ky, Bonnie
Marwick, Tom
Stout, Martin
Harkness, Allan
Steeds, Rick
Robinson, Shaun
Oxborough, David
Adlam, David
Stanway, Susannah
Rana, Bushra
Ingram, Thomas
Ring, Liam
Rosen, Stuart
Plummer, Chris
Manisty, Charlotte
Harbinson, Mark
Sharma, Vishal
Pearce, Keith
Lyon, Alexander R
Augustine, Daniel X
Ghosh, Arjun K
Ky, Bonnie
Marwick, Tom
Stout, Martin
Harkness, Allan
Steeds, Rick
Robinson, Shaun
Oxborough, David
Adlam, David
Stanway, Susannah
Rana, Bushra
Ingram, Thomas
Ring, Liam
Rosen, Stuart
Plummer, Chris
Manisty, Charlotte
Harbinson, Mark
Sharma, Vishal
Pearce, Keith
Lyon, Alexander R
Augustine, Daniel X
Citations
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Date
2021-03-03
Type
Article
Subject
Cardiology, Oncology. Pathology., Radiology
Citation
Dobson R, Ghosh AK, Ky B, Marwick T, Stout M, Harkness A, Steeds R, Robinson S, Oxborough D, Adlam D, Stanway S, Rana B, Ingram T, Ring L, Rosen S, Plummer C, Manisty C, Harbinson M, Sharma V, Pearce K, Lyon AR, Augustine DX. British Society for Echocardiography and British Cardio-Oncology Society guideline for transthoracic echocardiographic assessment of adult cancer patients receiving anthracyclines and/or trastuzumab. Echo Res Pract. 2021 Mar 31;8(1):G1-G18. doi: 10.1530/ERP-21-0001.
Journal / Source Title
Echo Research and Practice
DOI
10.1530/ERP-21-0001
PMID
34106116
Publisher
BMC
Publisher’s URL
https://echo.biomedcentral.com/