Cerebral hemodynamics at altitude: effects of hyperventilation and acclimatization on cerebral blood flow and oxygenation.
Sanborn, Matthew R Edsell, Mark E Kim, Meeri N Mesquita, Rickson Putt, Mary E Yow, Heng Wilson, Mark H Yodh, Arjun G Grocott, Mike Martin, Daniel S
Sanborn, Matthew R
Edsell, Mark E
Kim, Meeri N
Mesquita, Rickson
Putt, Mary E
Yow, Heng
Wilson, Mark H
Yodh, Arjun G
Grocott, Mike
Martin, Daniel S
Abstract
Objective: Alterations in cerebral blood flow (CBF) and cerebral oxygenation are implicated in altitude-associated diseases. We assessed the dynamic changes in CBF and peripheral and cerebral oxygenation engendered by ascent to altitude with partial acclimatization and hyperventilation using a combination of near-infrared spectroscopy, transcranial Doppler ultrasound, and diffuse correlation spectroscopy.
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Date
2015-03-18
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Wilderness Environ Med . 2015 Jun;26(2):133-41