Consensus on acromegaly complications: an update
Giustina, Andrea di Filippo, Luigi Fleseriu, Maria Pivonello, Rosario Petersenn, Stephan Wass, John Samson, Susan L Pereira, Alberto M Luque, Raúl M Biagetti, Betina
Giustina, Andrea
di Filippo, Luigi
Fleseriu, Maria
Pivonello, Rosario
Petersenn, Stephan
Wass, John
Samson, Susan L
Pereira, Alberto M
Luque, Raúl M
Biagetti, Betina
Abstract
The 16th Acromegaly Consensus Conference in September 2024 updated recommendations on diagnosis and treatment of acromegaly comorbidities. Since the 2020 acromegaly comorbidity management guideline was published, new evidence has emerged on novel and known comorbidities and new treatment approaches. Forty-three experts in the management of acromegaly reviewed the current literature and assessed changes in clinical practice standards and management. Current outcome goals were considered and updated, with a focus on the impact of current and emerging treatments of these comorbidities. Participants assessed factors that determine pharmacological choices, as well as use of specific agents in the management of the most relevant acromegaly comorbidities. We present consensus recommendations highlighting optimization of evidence-based acromegaly comorbidities management.
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Date
2026-04-29
Type
Article
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Citation
Giustina A, di Filippo L, Fleseriu M, Pivonello R, Petersenn S, Wass J, Samson SL, Pereira AM, Luque RM, Biagetti B, Zatelli MC, Ho KKY, Boguszewski CL, van der Lely AJ, Gurnell M, Biermasz N, Schilbach K, Ferone D, Gadelha MR, Ioachimescu AG, Ghigo E, Strasburger CJ, Kadioglu P, Maffei P, Karavitaki N, Marazuela M, Buchfelder M, Chiloiro S, Luger A, Greenman Y, Valassi E, Bernabeu I, Frara S, Chanson P, Brue T, Ayuk J, Casanueva FF, Colao A, Mortini P, Neggers S, Puig-Domingo M, Uygur MM, Melmed S. Consensus on acromegaly complications: an update. Pituitary. 2026 Apr 29;29(3):76. doi: 10.1007/s11102-026-01639-z.