Efficacy and safety of ciclosporin versus methotrexate in the treatment of severe atopic dermatitis in children and young people (TREAT): a multicentre, parallel group, assessor-blinded clinical trial
Flohr, Carsten ; Rosala-Hallas, Anna ; Jones, Ashley P ; Beattie, Paula ; Baron, Susannah ; Browne, Fiona ; Brown, Sara J ; Gach, Joanna E ; Greenblatt, Danielle ; Hearn, Ross ... show 10 more
Flohr, Carsten
Rosala-Hallas, Anna
Jones, Ashley P
Beattie, Paula
Baron, Susannah
Browne, Fiona
Brown, Sara J
Gach, Joanna E
Greenblatt, Danielle
Hearn, Ross
Abstract
Background: Conventional systemic drugs are used to treat children and young people (CYP) with severe atopic dermatitis (AD) worldwide, but no robust RCT evidence exists regarding their efficacy and safety in this population. While novel therapies have expanded therapeutic options, their high cost means traditional agents remain important, especially in lower resource settings.
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Date
2023-09-19
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Citation
Br J Dermatol . 2023 Sep 19;ljad281
