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Beyond gastroenteritis : a case of Salmonella infection leading to adrenal insufficiency
Abstract
Primary adrenal insufficiency (PAI), or Addison's disease, is a rare and potentially life-threatening condition that requires prompt diagnosis and management. While most cases are autoimmune, other causes include infections such as Salmonella, though this is rarely reported. We describe a case of bilateral adrenal abscesses and adrenal insufficiency secondary to disseminated Salmonella Saintpaul infection in a previously healthy 20-year-old male following travel to Thailand. This case highlights the importance of early recognition of adrenal involvement in septic patients with persistent fever and electrolyte imbalances, even in immunocompetent individuals.
Date
2025-10-13
Type
Article
Subject
Addison disease, Adrenal insufficiency, Bacterial infections, Salmonella infections
Collections
Citation
Wint Htal TT, Tin Hla AP, Paing AMM, Thura K, Pollard C. Beyond Gastroenteritis: A Case of Salmonella Infection Leading to Adrenal Insufficiency. Cureus. 2025 Oct 13;17(10):e94443. doi: 10.7759/cureus.94443.
Journal / Source Title
Cureus
DOI
10.7759/cureus.94443
PMID
41089578
Publisher
Springer
Publisher’s URL
https://pmc.ncbi.nlm.nih.gov/articles/PMC12516929/
Publisher’s statement
© Copyright 2025 Wint Htal et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.