Angioedema as a presenting feature in a patient with SLE : a case report
Parvaiz Rasheed, Tabinda Jabeen, Maryam Ahsan Iqbal, Sheikh Khurram Saleem, Muhammad Faizan Ejaz, Khawaja Akbar, Amna Jadoon, Sarosh K Saleem Khan, Mohammad
Parvaiz Rasheed, Tabinda
Jabeen, Maryam
Ahsan Iqbal, Sheikh
Khurram Saleem, Muhammad
Faizan Ejaz, Khawaja
Akbar, Amna
Jadoon, Sarosh K
Saleem Khan, Mohammad
Abstract
Systemic lupus erythematosus (SLE) is a multi-organ autoimmune disease that can be easily missed due to its variable presentation. Acquired angioedema (AAE) is a rare first presentation of SLE. We report a case of a 23-year-old woman who presented to the emergency department with rapidly progressive swelling of the tongue and neck, followed by respiratory discomfort and a generalized non-itchy rash. A tracheostomy was performed to relieve her symptoms. Her history, examination, and relevant investigations all indicated SLE. She was treated with high-dose steroids, and pulse therapy with methylprednisolone was given for three days. Hydroxychloroquine was added, but she developed sepsis and an acute flare of SLE secondary to tracheostomy site infection. Subsequently, she was treated with broad-spectrum antibiotics, followed by a tapering dose of steroids and a maintenance dose of azathioprine. She responded to treatment, tracheostomy reversal was performed, and the patient was discharged.
MIDER Authors
Affiliations
University Hospital Bristol and Weston NH Foundation Trust; The Dudley Group NHS Foundation Trust; District Headquarters Hospital et al
Citations
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Date
2024-10-20
Type
Collections
Citation
Parvaiz Rasheed T, Jabeen M, Ahsan Iqbal S, Khurram Saleem M, Faizan Ejaz K, Akbar A, Jadoon SK, Saleem Khan M. Angioedema as a Presenting Feature in a Patient With SLE: A Case Report. Cureus. 2024 Oct 20;16(10):e71939. doi: 10.7759/cureus.71939