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Tumour-induced osteomalacia.
Fernando, Devaka Nuam, Cing San Tun, Thein Zaw
Fernando, Devaka
Nuam, Cing San
Tun, Thein Zaw
Abstract
Phosphate is important for normal mineralisation of bone. Phosphate is important in its own right for neuromuscular function, and profound hypophosphataemia can be accompanied by encephalopathy, muscle weakness and cardiomyopathy. Hypophosphataemia can be due to intracellular uptake of phosphate from the extracellular fluid, reduced intestinal phosphate absorption, increased renal excretion, decreased renal tubular absorptive capacity and genetic defects in renal tubule phosphate transporters.
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Date
2022-07
Type
Article