Reduced Cardiovascular Reserve in Chronic Kidney Failure: A Matched Cohort Study.
Ting, Stephen M S Hamborg, Thomas Oxborough, David Lim, Kenneth Koganti, Sudheer Bland, Rosemary Fletcher, Simon Krishnan, Nithya S Higgins, Robert M Townend, Jonathan
Ting, Stephen M S
Hamborg, Thomas
Oxborough, David
Lim, Kenneth
Koganti, Sudheer
Bland, Rosemary
Fletcher, Simon
Krishnan, Nithya S
Higgins, Robert M
Townend, Jonathan
Abstract
Background: Patients with chronic kidney failure (CKF) experience impaired functional cardiovascular reserve with reduced oxygen consumption at peak exercise (VO(2peak)). No studies have examined whether this is related to impaired cardiovascular compliance as a consequence of loss of adaptive structural alterations, resulting from chronic uremia or hypertension.
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Date
2015-04-18
Type
Article
Subject
Human physiology, Nephrology/Renal medicine, Cardiology
Citation
Ting SM, Hamborg T, McGregor G, Oxborough D, Lim K, Koganti S, Aldridge N, Imray C, Bland R, Fletcher S, Krishnan NS, Higgins RM, Townend J, Banerjee P, Zehnder D. Reduced Cardiovascular Reserve in Chronic Kidney Failure: A Matched Cohort Study. Am J Kidney Dis. 2015 Aug;66(2):274-84. doi: 10.1053/j.ajkd.2015.02.335. Epub 2015 Apr 18.
Journal / Source Title
American Journal of Kidney Diseases
DOI
10.1053/j.ajkd.2015.02.335
PMID
25900597
Publisher
Elsevier