2026 Updated good practice recommendations for outpatient parenteral antimicrobial therapy (OPAT) in adults and children in the UK.
Noble, Ann L Patel, Sanjay Birnie, Ellie Dorgan, Eileen Durojaiye, Oyewole C Emilie, Caroline Guleri, Achyut Green, Helen Hedderwick, Sara Hinds, Lucy
Noble, Ann L
Patel, Sanjay
Birnie, Ellie
Dorgan, Eileen
Durojaiye, Oyewole C
Emilie, Caroline
Guleri, Achyut
Green, Helen
Hedderwick, Sara
Hinds, Lucy
Abstract
Good practice recommendations (GPRs) for outpatient parenteral antimicrobial therapy (OPAT) in the UK were first published in 2012 and 2015 for adult and paediatric OPAT, respectively, and then updated in 2019 as a combined set of recommendations for OPAT in all age groups. Since then, there has been ongoing expansion in national and global experience of OPAT. Here, we provide updated 2026 GPRs developed through a further review of the literature, expert consensus, and extensive consultation. As previously, these updated GPRs for OPAT in adults and children will support delivery of safe and effective OPAT by providing a set of quality indicators for OPAT in the UK regardless of the setting or service model.
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Affiliations
University Hospital Monklands, NHS Lanarkshire; Southampton Children's Hospital; University Hospitals of Derby and Burton NHS Foundation Trust; Northern Health and Social Care Trust, Antrim; Sheffield Teaching Hospitals NHS Foundation Trust; Service des Maladies Infectieuses et Tropicales, Metz, France; Mid Yorkshire Teaching Hospital NHS Trust, Wakefield; Craigavon Area Hospital, Portadown; Sheffield Children's Hospital NHS Foundation Trust; Beth Israel Deaconess Medical Center, Boston, USA; NHS Lothian, Edinburgh; The University of Queensland, Brisbane, Australia; Public Health Wales, Cardiff; South Warwickshire University NHS Foundation Trust; Buckinghamshire Healthcare NHS Trust, Aylesbury; Imperial College Healthcare NHS Trust, London; Imperial College London; NHS Greater Glasgow and Clyde
Date
2026-04-22
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Article
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Citation
Noble AL, Patel S, Birnie E, Dorgan E, Durojaiye OC, Emilie C, Guleri A, Green H, Hedderwick S, Hinds L, Mahoney MV, McIntyre K, Sime FB, Seddon O, Statham J, Woodley M, Gilchrist M, Seaton RA. 2026 Updated good practice recommendations for outpatient parenteral antimicrobial therapy (OPAT) in adults and children in the UK. JAC Antimicrob Resist. 2026 Apr 22;8(2):dlag044. doi: 10.1093/jacamr/dlag044.
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