New insulins and newer insulin regimens : a review of their role in improving glycaemic control in patients with diabetes
Setty, S Gururaj Crasto, W Jarvis, J Khunti, K Davies, M J
Setty, S Gururaj
Crasto, W
Jarvis, J
Khunti, K
Davies, M J
Abstract
The legacy effect of early good glycaemic control in people with diabetes shows it is associated with reduction of microvascular and macrovascular complications. Insulin therapy is essential and lifesaving in individuals with type 1 diabetes and beneficial for those with type 2 diabetes who fail to achieve optimal glycaemic targets with other classes of glucose-lowering therapies. Since the introduction of insulin analogues, insulin management has changed. This follow-up review attempts to update our earlier publication from 2009 and discusses the role of new insulin analogues and newer insulin regimens. Recognising the advent of new quality and economic initiatives both in the UK and worldwide, this paper reviews current insulin prescribing and the pros and cons of prescribing analogues in comparison to the human insulins that are now gaining more acceptance in everyday clinical practice.
MIDER Authors
Affiliations
University Hospitals of Leicester NHS Trust; George Eliot Hospital NHS Trust, Nuneaton; University of Leicester
Citations
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Date
2016-03
Type
Article
Subject
Collections
Citation
Gururaj Setty S, Crasto W, Jarvis J, Khunti K, Davies MJ. New insulins and newer insulin regimens: a review of their role in improving glycaemic control in patients with diabetes. Postgrad Med J. 2016 Mar;92(1085):152-64. doi: 10.1136/postgradmedj-2015-133716. Epub 2016 Feb 3.