Case report : Old World mucosal leishmaniasis : report of five imported cases to the Hospital for Tropical Diseases, London, United Kingdom
Patel, Trupti A. Scadding, Glenis K. Phillips, David E. Lockwood, Diana N.
Patel, Trupti A.
Scadding, Glenis K.
Phillips, David E.
Lockwood, Diana N.
Abstract
Old World species of Leishmania typically cause visceral and cutaneous leishmaniasis. Mucosal involvement is typically seen with infection by Leishmania species found in South America, usually after the healing of cutaneous leishmaniasis. We present five imported cases of mucosal leishmaniasis caused by Old World Mediterranean Leishmania infantum exclusively affecting the nasal mucosa or vocal cord. In only one case was there a recollection of a preceding cutaneous lesion compatible with cutaneous Leishmaniasis. Of significance was that four out of five cases were receiving local corticosteroids for chronic lung disorders and four were systemically immunosuppressed. This report highlights the importance of considering mucosal leishmaniasis in the differential diagnosis in those presenting with upper respiratory tract mucosal lesions with a relevant travel history to the Mediterranean and in whom malignancy has been excluded.
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Date
2017-07-24
Type
Article
Subject
Communicable diseases, Ear, Nose & Throat
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Citation
Patel TA, Scadding GK, Phillips DE, Lockwood DN. Case Report: Old World Mucosal Leishmaniasis: Report of Five Imported Cases to the Hospital for Tropical Diseases, London, United Kingdom. Am J Trop Med Hyg. 2017 Oct;97(4):1116-1119. doi: 10.4269/ajtmh.17-0162.
Journal / Source Title
The American Journal of Tropical Medicine and Hygiene
DOI
10.4269/ajtmh.17-0162
PMID
29031288
Publisher
American Society of Tropical Medicine and Hygiene
Publisher’s URL
https://pmc.ncbi.nlm.nih.gov/articles/PMC5637608/