The potential blunting effect of metformin and/or statin therapy on physical activity-induced associations with HbA1c in type 2 diabetes
Henson, Joseph Davies, Melanie J. Brady, Emer M. Edwardson, Charlotte L. Hall, Andrew P. Khunti, Kamlesh Redman, Emma Rowlands, Alex V. Sargeant, Jack Yates, Thomas
Henson, Joseph
Davies, Melanie J.
Brady, Emer M.
Edwardson, Charlotte L.
Hall, Andrew P.
Khunti, Kamlesh
Redman, Emma
Rowlands, Alex V.
Sargeant, Jack
Yates, Thomas
Abstract
Highlights Our analysis indicates a potential blunting effect of metformin and/or statin therapy on physical activity-induced associations with HbA1c. The benefit of daily physical activity on glycemic control in people with type 2 diabetes is potentially more apparent in those prescribed neither metformin nor statin therapy. As physical activity is rarely prescribed in isolation of other background medications used to manage type 2 diabetes, the results of this analysis may help to maximize interventions delivered through routine clinical care, while allowing for personalization in prescribed physical activity and pharmacotherapy.
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Date
2023-11-14
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Henson, J., Davies, M. J., Brady, E. M., Edwardson, C. L., Hall, A. P., Khunti, K., Redman, E., Rowlands, A. V., Sargeant, J., & Yates, T. (2023). The potential blunting effect of metformin and/or statin therapy on physical activity-induced associations with HbA1c in type 2 diabetes. Journal of diabetes, 10.1111/1753-0407.13495. Advance online publication. https://doi.org/10.1111/1753-0407.13495