British Society for Immunology and United Kingdom Primary Immunodeficiency Network (UKPIN) consensus guideline for the management of immunoglobulin replacement therapy
Grigoriadou, S Clubbe, R Garcez, T Huissoon, A Grosse-Kreul, D Jolles, S Henderson, K Edmonds, J Lowe, D Bethune, C
Grigoriadou, S
Clubbe, R
Garcez, T
Huissoon, A
Grosse-Kreul, D
Jolles, S
Henderson, K
Edmonds, J
Lowe, D
Bethune, C
Abstract
Currently, there is no guideline to support the use of immunoglobulin replacement therapy (IgRT) in primary and secondary immunodeficiency disorders in UK. The UK Primary Immunodeficiency Network (UK-PIN) and the British Society of Immunology (BSI) joined forces to address this need. Given the paucity of evidence, a modified Delphi approach was used covering statements for the initiation, monitoring, discontinuation of IgRT as well as home therapy programme. A group of six consultant immunologists and three nurse specialists created the statements, reviewed responses and feedback and agreed on final recommendations. This guideline includes 22 statements for initiation, 22 statements for monitoring, 11 statement for home therapy, and 19 statements for discontinuation of IgRT. Further areas of research are proposed to improve future delivery of care.
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Date
2022-08-04
Type
Article
Subject
Collections
Citation
Grigoriadou S, Clubbe R, Garcez T, Huissoon A, Grosse-Kreul D, Jolles S, Henderson K, Edmonds J, Lowe D, Bethune C. British Society for Immunology and United Kingdom Primary Immunodeficiency Network (UKPIN) consensus guideline for the management of immunoglobulin replacement therapy. Clin Exp Immunol. 2022 Oct 21;210(1):1-13. doi: 10.1093/cei/uxac070.
Journal / Source Title
Clinical and Experimental Immunology
DOI
10.1093/cei/uxac070
PMID
35924867
Publisher
Oxford University Press
Publisher’s URL
https://academic.oup.com/cei