Levothyroxine in Women with Thyroid Peroxidase Antibodies before Conception.
Abstract
Thyroid peroxidase antibodies are associated with an increased risk of miscarriage and preterm birth, even when thyroid function is normal. Small trials indicate that the use of levothyroxine could reduce the incidence of such adverse outcomes.
Author
Dhillon-Smith, Rima K
Middleton, Lee J
Sunner, Kirandeep K
Cheed, Versha
Baker, Krys
Farrell-Carver, Samantha
Bender-Atik, Ruth
Agrawal, Rina
Bhatia, Kalsang
Edi-Osagie, Edmond
Gupta, Pratima
Jurkovic, Davor
Khalaf, Yacoub
MacLean, Marjory
McCabe, Christopher
Mulbagal, Khashia
Nunes, Natalie
Overton, Caroline
Rai, Raj
Raine-Fenning, Nick
Robinson, Lynne
Ross, Jackie
Sizer, Andrew
Small, Rachel
Tan, Alex
Underwood, Martyn
Kilby, Mark D
Boelaert, Kristien
Daniels, Jane
Thangaratinam, Shakila
Chan, Shiao Y
Coomarasamy, Arri
Quenby, Siobhan
Ghobara, Tarek
Middleton, Lee J
Sunner, Kirandeep K
Cheed, Versha
Baker, Krys
Farrell-Carver, Samantha
Bender-Atik, Ruth
Agrawal, Rina
Bhatia, Kalsang
Edi-Osagie, Edmond
Gupta, Pratima
Jurkovic, Davor
Khalaf, Yacoub
MacLean, Marjory
McCabe, Christopher
Mulbagal, Khashia
Nunes, Natalie
Overton, Caroline
Rai, Raj
Raine-Fenning, Nick
Robinson, Lynne
Ross, Jackie
Sizer, Andrew
Small, Rachel
Tan, Alex
Underwood, Martyn
Kilby, Mark D
Boelaert, Kristien
Daniels, Jane
Thangaratinam, Shakila
Chan, Shiao Y
Coomarasamy, Arri
Quenby, Siobhan
Ghobara, Tarek
Citations
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Date
2019-03-23
Type
Article
Subject
Obstetrics. Midwifery
Citation
N Engl J Med . 2019 Apr 4;380(14):1316-1325
Journal / Source Title
The New England Journal of Medicine
DOI
10.1056/NEJMoa1812537
PMID
30907987
Publisher
Massachusetts Medical Society