Adenoid cystic carcinoma of the thymus gland
Shatila, Mohamed Hemead, Hanan Murukesh, Nishanth Taniere, Philippe Russell, Caroline Menon, Ashvini Patel, Akshay J
Shatila, Mohamed
Hemead, Hanan
Murukesh, Nishanth
Taniere, Philippe
Russell, Caroline
Menon, Ashvini
Patel, Akshay J
Abstract
Background: Thymic carcinomas are rare and aggressive tumours. They constitute a heterogeneous group of tumours with various histological patterns and subtypes resembling epithelial tumours arising from other organs.
Case presentation: We hereby represent a case of primary thymic carcinoma with adenoid cystic carcinoma-like features (TCACC) which is an extremely rare variant of thymic adenocarcinoma. To date and to the best of our knowledge, there are nine reported cases in literature and ours is the tenth. Our case was treated surgically but the implementation of adjuvant chemoradiotherapy has been reported in few of the published cases.
Conclusions: TCACC constitutes a rare entity of thymic adenocarcinoma with limited available literature. The current data is derived from few case reports and case series. The histological overlap of these tumours and primary ACC of salivary glands poses a diagnostic challenge. Radiological investigations, immunohistochemical phenotyping and genetic analysis are crucial in establishing the diagnosis.
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Date
2023-11-09
Type
Article
Subject
Surgery, Oncology. Pathology.
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Citation
Shatila, M., Hemead, H., Murukesh, N., Taniere, P., Russell, C., Menon, A., & Patel, A. J. (2023). Adenoid cystic carcinoma of the thymus gland. Journal of cardiothoracic surgery, 18(1), 307. https://doi.org/10.1186/s13019-023-02432-w
Journal / Source Title
Journal of Cardiothoracic Surgery
DOI
10.1186/s13019-023-02432-w
PMID
37946236
Publisher
BMC
Publisher’s URL
https://cardiothoracicsurgery.biomedcentral.com/