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Pharmacogenomics to optimise psychotropic prescribing : a survey of mental health professionals’ perceptions, knowledge, and educational needs

Abstract
A survey was conducted to determine attitudes, knowledge, and educational needs of mental health professionals regarding pharmacogenomics. We recruited 128 clinicians working in mental health in England, and we assessed their experiences using an adapted version of the “U‐PGx Clinician’s Questionnaire”. Responding clinicians had positive attitudes towards pharmacogenomics testing, although they lacked confidence in ordering and interpreting tests, for which most had never received any formal training. Only 6% of clinicians answered all 4 knowledge testing questions correctly, and barriers to clinical implementation included lack of familiarity and knowledge for several pharmacogenomics concepts, such as drug metabolism and genetics, as well as needing support from their working institution. Looking ahead, we found that accredited workshops and patient cases were preferred learning formats, and we suggest tailored education programmes to enable mental health professionals to apply pharmacogenomics in clinical practice.
Author
Panconesi, Daniele
Murtough, Stephen
Cotic, Marius
Khani, Noushin Saadullah
Varney, Lauren
Richards-Brown, Maria
Abidoph, Rosemary
Mills, Daisy
Richards-Belle, Alvin
Molai, Jazmin
Fenwick, James
Curwen, Joanna
Allin, Matthew
Berry, Alex
Barczyk, Magdalana
Bonaccorso, Stefania
Griffiths, Rebecca
Bernini, Massimo
Kumar, Ajai
Senthilkumar, Suruthy
Dawda, Yogita
Murdoch, Rosie
Crane, Jamie
Rahimi, Yousuf
Howard, Myles
Welfare-Wilson, Alison
Secchi, Agostina
Thomas, Carmel
Pastor, Bethany
Sharma, Parveen
Pius, Georgy
Nazir, Rashad
Mir, Asif
Cheshire, Jack
Bostock, Rhianne
Gibbon, Simon
Singh, Pratima
Shah, Chetan
Richards, Sabrina
Cheung, Sai-Bo
Rowe-Leete, Louise
Jibero, Anita
Cox, Rebecca
Van Driel, Philip
Bramon, Elvira
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Date
2026
Type
Article
Subject
Pharmacology, Genetics, Drug therapy, Mental health
Collections
NottsHC Medicines Management
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Citation
Panconesi, D., Murtough, S., Cotic, M., Khani, N. S., Varney, L., Richards-Brown, M., Abidoph, R., Mills, D., Richards-Belle, A., Molai, J., et al. (2026). Pharmacogenomics to optimise psychotropic prescribing : a survey of mental health professionals’ perceptions, knowledge, and educational needs. The Pharmacogenomics Journal, 26 (1), pp.2.
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DOI
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https://mider.dspace7.openrepository.com/handle/20.500.12904/20110
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Publisher
Nature Publishing Group
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Publisher’s statement
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http:// creativecommons.org/licenses/by/4.0/. © The Author(s) 2026
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