Monitoring thyroid function during amiodarone use.
Abstract
Amiodarone is an antiarrhythmic drug used to treat cardiac tachyarrhythmias. It has many adverse effects, with thyroid dysfunction one of the most notable. Through various mechanisms, both thyrotoxicosis and hypothyroidism can occur secondary to amiodarone therapy. There are two types of amiodarone-induced thyrotoxicosis: type 1 occurs in those with pre-existing thyroid disease and is treated with thionamide, whereas type 2 occurs in those without and is treated with glucocorticoids. Patients with amiodarone-induced hypothyroidism may be given levothyroxine to replace thyroid hormone, but in some cases, the appropriate management may be cessation of amiodarone.
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Date
2024-01
Type
Article
Subject
Amiodarone, Hypothyroidism, Thyroid, Thyrotoxicosis, Thyroxine
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Citation
Sharma, P. et al. (2024) ‘Monitoring thyroid function during amiodarone use’, British Journal of Hospital Medicine (17508460), 85(1), pp. 1–5
Journal / Source Title
DOI
PMID
Publisher
British Journal of Hospital Medicine