The results of ProHCL: Patient-reported outcomes in people living with type 1 diabetes on hybrid closed-loop insulin pump therapy - experiences from the NHS England pilot
Griffin, Tomas Hagan, Jennifer Chauhan, Radhika Crabtree, Thomas Ackroyd, Dawn Elliott, Jackie Narendran, Parth Bawlchhim, Zosanglura Hadjiconstantinou, Michelle Choudhary, Pratik
Griffin, Tomas
Hagan, Jennifer
Chauhan, Radhika
Crabtree, Thomas
Ackroyd, Dawn
Elliott, Jackie
Narendran, Parth
Bawlchhim, Zosanglura
Hadjiconstantinou, Michelle
Choudhary, Pratik
Abstract
AIMS: This study evaluated the impact of ≥3 months of HCL use on patient-reported outcomes (PROs) in PwT1D and their partners. METHODS: Participants enrolled on the NHS England HCL pilot were invited to take part in a mixed-methods study. Here, we present the results of the quantitative study. PwT1D completed online questionnaires, including INSPIRE (0-100), DTSQc (-18 to +18), System Usability Scale (0-100), and bespoke measures. Self-reported clinical data were collected. Optionally, partners completed the INSPIRE for partners questionnaire. RESULTS: A total of 125 PwT1D and 33 partners participated. PROs included: INSPIRE 88/100 (IQR 73-95) and DTSQc 17/18(14-18). In INSPIRE, >70 % strongly agree that HCL improved HbA1c, time in range and overall quality of life. In DTSQc, >70 % noted that their blood glucose levels had been unacceptably low/high much less of the time since starting HCL. However, 54.4 % reported increased alarm burden and 21.6 % information overload. People who found HCL harder to use based on the SUS score had lower INSPIRE, DTSQs and DTSQc scores and higher HbA1c than those who found HCL easier to use. CONCLUSIONS: HCL therapy is associated with improved PROs in PwT1D. However, system usability significantly influences outcomes, and alarm and data burden remain concerns.
MIDER Authors
Affiliations
University Hospitals of Derby & Burton NHS Foundation Trust
Date
2026-02
Type
Article
Subject
Collections
Citation
Griffin TP, Hagan J, Chauhan R, Crabtree TS, Ackroyd D, Elliott J, Narendran P, Bawlchhim Z, Wilmot EG, Hadjiconstantinou M, Choudhary P. The results of ProHCL: Patient-reported outcomes in people living with type 1 diabetes on hybrid closed-loop insulin pump therapy - experiences from the NHS England pilot. Diabetes Res Clin Pract. 2026 Feb;232:113084. doi: 10.1016/j.diabres.2026.113084. Epub 2026 Jan 6. Erratum in: Diabetes Res Clin Pract. 2026 Mar 17:113170. doi: 10.1016/j.diabres.2026.113170.