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A rare case of Paget's disease affecting the cervical spine.

Klezl, Zdenek
Abstract
We present the case of a 75-year-old man with a rapidly progressive cervical myelopathy on a background of a 3-year history of neck pain and a severely degenerative cervical spine. The patient developed progressive myelopathy over a six-month period and suffered from worsening kyphosis. Suspicion of an underlying oncological process prompted transfer to our tertiary referral unit. Biopsy was consistent for Paget's disease, an extremely rare diagnosis of the cervical spine. Magnetic resonance imaging revealed cord compression between C4 and C6 with associated cord signal change indicative of myelopathy. A three-level corpectomy and posterior instrumented fusion was performed. There was significant blood loss (3.5l) intraoperatively, consistent with a diagnosis of Paget's disease of the bone. Cell salvage was used, as was neuromonitoring for both the anterior and posterior part of the procedure. Postoperatively, neurological function improved slightly and the patient required community neurorehabilitation to allow independent living.
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Date
2019-02
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Article
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Ann R Coll Surg Engl. 2019 Feb;101(2):e38-e42. doi: 10.1308/rcsann.2018.0187. Epub 2018 Oct 16.
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No Pre or Post-Print Version. 12 month embargo on PDF
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