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Rotavirus infection in children with acute gastroenteritis in Iran: a systematic review and meta-analysis
Moradi-Lakeh, Maziar Shakerian, Sareh Yaghoubi, Mohsen Esteghamati, Abdoulreza Shokraneh, Farhad Baradaran, Hamid-Reza Ghanaee, Roxana M
Moradi-Lakeh, Maziar
Shakerian, Sareh
Yaghoubi, Mohsen
Esteghamati, Abdoulreza
Shokraneh, Farhad
Baradaran, Hamid-Reza
Ghanaee, Roxana M
Abstract
Background: The recent studies show that Rotavirus is important cause of the acute gastroenteritis. The aim of this review is to estimate the number of Rotavirus infection among Iranian children by performing a systematic review and estimating a pooled data.; Methods: We performed a systematic literature review in relevant databases including PUBMED, MEDLINE, OVID, SID, MAGIRAN, and IRANMEDEX. Search in databases was done in October 10, 2013. Meta-analysis was performed using the STATA statistical package version 11. We assessed heterogeneity by Q-test and used random model for pooling measures of proportion of Rotavirus infection among Iranian children with diarrhea (and 95% confidence intervals [CI]). Sub group analysis between in-patient and outpatient group were done and publication bias was assessed by Egger and Begg tests.; Results: A total of 154 records were identified in our searching. There were 36 studies including a total of 15,368 children with diarrhea. Out of 15,368 children, 6,338 were positive for Rotavirus gastroenteritis. Overall pooled estimate of infection with Rotavirus among cases of gastroenteritis was 0.35 (95% CI, 0.28-0.41). Pooled estimates for hospitalized children and outpatient subgroups were 0.39 (95% CI, 0.30-0.48), and 0.31 (95% CI, 0.23-0.38), respectively.; Conclusions: This study supports the importance of Rotavirus in the Iranian population such as common cause of diarrhea among children. Therefore, decision to adopt immunization programs to prevent Rotavirus infection might be helpful in Iran.;
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Date
2014-07-06
Type
Article
Subject
Gastroenteritis, Reoviridae
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Citation
Moradi-Lakeh M, Shakerian S, Yaghoubi M, Esteghamati A, Shokraneh F, Baradaran HR, Ghanaee RM. Rotavirus Infection in Children with Acute Gastroenteritis in Iran: A Systematic Review and Meta-analysis. Int J Prev Med. 2014 Oct;5(10):1213-23.
Journal / Source Title
International Journal of Preventive Medicine
DOI
PMID
25400878
Publisher
Isfahan University of Medical Sciences
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Publisher’s statement
© International Journal of Preventive Medicine
This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.