Silent hypoxia is not an identifiable characteristic in patients with COVID-19 infection
Abstract
BACKGROUND: We aimed to assess whether asymptomatic ("happy") hypoxia was an identifiable physiological phenotype of COVID-19 acute respiratory distress syndrome (ARDS), and associated with need for ICU admission. METHODS: We performed an observational cohort study of all adult patients admitted with hypoxaemic respiratory failure to a large acute hospital Trust serving the East Midlands, UK. Patients with confirmed COVID-19 were compared to those without. Physiological response to hypoxaemia was modelled using a linear mixed effects model. RESULTS: Of 1,586 patients included, 75% tested positive for SARS-CoV-2. The ROX index was 2.08 min-1 lower (1.56-2.61, p lower (1.56-2.61, p Copyright © 2022 Elsevier Ltd. All rights reserved.
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Date
2022
Type
Article
Subject
Acute respiratory distress syndrome, COVID-19, Hypoxaemia, Hypoxia
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Plummer, N.R., Fogarty, A., Shaw, D., Card, T. R., West, J. and Crooks, C. J. (2022) 'Silent hypoxia is not an identifiable characteristic in patients with COVID-19 infection', Respiratory medicine, 197, pp. 106858. doi: 10.1016/j.rmed.2022.106858 https://doi.org/10.1016/j.rmed.2022.106858.
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Available to read on the publisher's website here: https://doi.org/10.1016/j.rmed.2022.106858