Chlorpromazine vs reserpine for schizophrenia
Abstract
To review the effects of chlorpromazine vs reserpine for schizophrenia. Judged by standards of today, evidence is largely of limited quality. However, some studies of the 1950s are remarkable in their foresight and clarity. Reserpine did have effect on "global state"—but chlorpromazine did seem to perform better. Important issues regarding adverse effects were not really picked up by these trials. Chlorpromazine remains on the WHO list of essential drugs. Reserpine is now almost obsolete—and, again, this seems justified—although, reserpine has largely fallen into disuse probably as a result of evidence other than that reported in the pioneering trials used in this review. (PsycINFO Database Record (c) 2016 APA, all rights reserved)
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Date
2016
Type
Article
Subject
Drug therapy, Schizophrenia
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Citation
Nur, S. & Adams, C. E. (2016). Chlorpromazine vs reserpine for schizophrenia. Schizophrenia Bulletin, 42 (3), pp.550-551.