The effect of exercise training on adipose tissue insulin sensitivity: A systematic review and meta-analysis
Aithal, Guruprasad P.
Aithal, Guruprasad P.
Abstract
This systematic review and meta-analysis determined the impact of exercise training on adipose tissue insulin sensitivity in adults. Its scope extended to studies measuring whole-body and localized subcutaneous adipose tissue insulin sensitivity using validated techniques. Consensus from four studies demonstrates that exercise training improved whole-body adipose tissue insulin sensitivity when measured via stable-isotope lipid tracers (rate of appearance suppression in response to hyperinsulinemia). Meta-analysis of 20 studies (26 intervention arms) employing the adipose tissue insulin resistance index (ADIPO-IR) supported these findings (-10.63 [-14.12 to -7.15] pmol.L-1 x mmol.L-1). With ADIPO-IR, this response was greater in studies documenting weight loss and shorter sampling time (). With ADIPO-IR, this response was greater in studies documenting weight loss and shorter sampling time (Copyright © 2022 World Obesity Federation.
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Date
2022
Type
Article
Subject
Systematic review, Exercise, Adipose tissue, Insulin resistance, Weight loss
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Citation
Engin, B., Willis, S.A., Malaikah, S., Sargeant, J.A., Yates, T., Gray, L.J., Aithal, G.P., Stensel, D.J. and King, J.A. (2022) 'The effect of exercise training on adipose tissue insulin sensitivity: A systematic review and meta-analysis', Obesity Reviews, 23(7), pp. e13445. doi: 10.1111/obr.13445 https://doi.org/10.1111/obr.13445.