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Ensemble Kalman inversion for magnetic resonance elastography
McGrath, Deirdre M. Francis, Susan T.
McGrath, Deirdre M.
Francis, Susan T.
Abstract
Magnetic resonance elastography (MRE) is an MRI-based diagnostic method for measuring mechanical properties of biological tissues. MRE measurements are processed by an inversion algorithm to produce a map of the biomechanical properties. In this paper a new and powerful method (ensemble Kalman inversion with level sets (EKI)) of MRE inversion is proposed and tested. The method has critical advantages: material property variation at disease boundaries can be accurately identified, and uncertainty of the reconstructed material properties can be evaluated by consequence of the probabilistic nature of the method. EKI is tested in 2D and 3D experiments with synthetic MRE data of the human kidney. It is demonstrated that the proposed inversion method is accurate and fast. Copyright Creative Commons Attribution license.
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Date
2022
Type
Article
Subject
Elasticity imaging techniques, Magnetic resonance imaging
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Citation
Iglesias, M., McGrath, D.M., Tretyakov, M.V. and Francis, S.T. (2022) 'Ensemble Kalman inversion for magnetic resonance elastography', Physics in Medicine & Biology, 67(23), pp. 11 25. doi: 10.1088/1361-6560/ac9fa1 https://doi.org/10.1088/1361-6560/ac9fa1.