The potential blunting effect of metformin and/or statin therapy on physical activity-induced associations with HbA1c in type 2 diabetes
Abstract
Highlights Our analysis indicates a potential blunting effect of metformin and/or statin therapy on physical activity-induced associations with HbA1c. The benefit of daily physical activity on glycemic control in people with type 2 diabetes is potentially more apparent in those prescribed neither metformin nor statin therapy. As physical activity is rarely prescribed in isolation of other background medications used to manage type 2 diabetes, the results of this analysis may help to maximize interventions delivered through routine clinical care, while allowing for personalization in prescribed physical activity and pharmacotherapy.
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Date
2023-11-14
Type
Article
Subject
metformin, physical activity, statins, type 2 diabetes
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Citation
Henson, J., Davies, M. J., Brady, E. M., Edwardson, C. L., Hall, A. P., Khunti, K., Redman, E., Rowlands, A. V., Sargeant, J., & Yates, T. (2023). The potential blunting effect of metformin and/or statin therapy on physical activity-induced associations with HbA1c in type 2 diabetes. Journal of diabetes, 10.1111/1753-0407.13495. Advance online publication. https://doi.org/10.1111/1753-0407.13495