Extrapulmonary nontuberculous mycobacterial infections: a guide for the general physician
Abstract
Non-tuberculous mycobacteria (NTM) infections predominantly present as pulmonary disease. Although relatively rare, 20-30 % originate from extrapulmonary sites resulting in a wide range of clinical syndromes. Immunocompromised individuals are particularly susceptible. Clinical manifestations include skin and soft-tissue infections, lymphadenitis, musculoskeletal infections and disseminated disease. Diagnosing extrapulmonary NTM is challenging, and management is complex, often involving multiple radiological and microbiological investigations, long courses of combination antibiotic regimens and may require adjuvant surgical interventions. We highlight both the importance of involving NTM experts at an early stage and the role of a multidisciplinary approach in the diagnosis and management of these infections.
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Date
2024-01
Type
Article
Subject
Disseminated, Extrapulmonary, Localised, Non-tuberculous mycobacteria infection
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Citation
Malhotra, A. M., Arias, M., Backx, M., Gadsby, J., Goodman, A., Gourlay, Y., Milburn, H., Moncayo-Nieto, O. L., Shimmin, D., Dedicoat, M., & Kunst, H. (2024). Extrapulmonary nontuberculous mycobacterial infections: a guide for the general physician. Clinical medicine (London, England), 24(1), 100016. https://doi.org/10.1016/j.clinme.2024.100016